Alekha K. Dash, RPh, PhD
Alekha K. Dash, RPh, PhD

Alekha K. Dash, RPh, PhD

Professor
Endowed Chair, Gilbert F. Taffe, Jr. Endowed Chair - Holder of Gilbert F. Taffe, Jr. Endowed Chair
Chair, Department of Pharmacy Sciences - Chair, Department of Pharmacy Sciences, Creighton University, Omaha, Nebraska.
Associate Dean, Research - Associate Dean for Research, School of Pharmacy and Health Professions, Creighton University, Omaha, Nebraska.
School of Pharmacy and Health Professions

Academic Appointments

Department

  • Pharmacy Sciences

Position

  • Professor

Secondary Appointment

  • School of Medicine

Teaching Activity

  • MPS 691 - Pharmaceutical Sciences Seminar, 2014-Present
  • MPS 692 - Directed Independent Study - MPS Program - 1995-Present
  • MPS 693 - Directed Independent Research - MPS Program - 1995-Present
  • MPS 799 - Master's Thesis, 1995-Present
  • PHA 327 - Pharmaceutics II, 2001-2011

Publications and Presentations

Books

  • Mohapatra, S.K. and Dash, A.K., Chapter 12: Special Dosage Forms and Drug Delivery Systems, in Pharmaceutics: Basic Principles and Application to Pharmacy Sciences (2013), Eds. AK Dash, S Singh and J Tolman, Elsevier, 2013, 273-303, 2013
  • Dash, A.K., Chapter 8: Solid Dosage Forms, in Pharmaceutics: Basic Principles and Application to Pharmacy Sciences (2013), Eds. AK Dash, S Singh and J Tolman, Elsevier, 2013, 161-180, 2013
  • Dash, A.K., Chapter 7: Drug, Dosage Form and Drug Delivery Systems, in Pharmaceutics: Basic Principles and Application to Pharmacy Sciences (2013), Eds. AK Dash, S Singh and J Tolman, Elsevier, 2013, 153-159, 2013
  • Singh S. and Dash, A.K., Chapter 3: Physical Properties, Their Determination and Importance in Pharmaceutics, in Pharmaceutics: Basic Principles and Application to Pharmacy Sciences (2013), Eds. AK Dash, S Singh and J Tolman, Elsevier, 2013, 51-84, 2013
  • Dash, A.K., Khurana, J., Singh, S., Multiple Emulsions: An overview and Pharmaceutical Applications in Colloids in Pharmaceutical and Biotechnological Applications, Edited by Monzer Fanun, Ph.D. CRC Press, 2010, Surfactant Science Series, CRC Press- Taylor and Francis Group, 148, 177-202, 2013

Articles

  • Meerovich, Smith, D.D. and Dash, A.K., Direct solid-phase peptide synthesis on chitosan microparticles for targeting tumor cells     https: doi.org/10.1016/j,jddst.2019.101288, Journal of Drug Delivery Science and Technology, 54, 2019
  • Meerovich, I. Nichols, M.G. and Dash, A.K., Low-intensity light-induced paclitaxel release from lipid-based nano-delivery systems   https: doi.org/10.1080/1061186x.2019.1571066, Journal of Drug Targeting, 27(9), 971-983, 2019
  • Nayak, R., Meerovich, I. and Dash, A.K., Translational multi-disciplinary approach for the drug and gene delivery systems for cancer treatment   https://doi.org/10.1208/s12249-019-1367-2, AAPS PharmSciTech, 20, 2019
  • Deodhar, S. and Dash, A.K., Long circulating liposomes: challenges and opportunities, Therapeutic Delivery, 9(12), 849-855, 2018
  • Bhujbal, S., and Dash, A.K., Metformin-Loaded Hyaluronic Acid Nanostructure for Oral Delivery
    DOI: 10.1208/s12249-018-1085-1, AAPS PharmSciTech, 19, 2543-2553, 2018
  • Saralkar, P., and Dash, A.K., Alginate nanoparticle containing curcumin and resveratrol: preparation, characterization and in vitro evaluation against DU145 Prostate Cancer Cell line  doi: 10.1208/s12249-017-0772-7, AAPS PharmSciTech, 18(7), 2814-2823, 2017
  • Patil, A., Singh, S., Opere, C., and Dash, A.K., Sustained-Release Delivery System of a Slow Hydrogen Sulfide Donor, GYY 4137, for Potential Application in Glaucoma   doi:10.1208/s12249-017-0712-6, AAPS PharmSciTech, 18, 2291-2302, 2017
  • Chauhan, H., Mohapatra, S., Munt, D., Chandratre, S., and Dash, A.K., Physical Chemical Characterization and Formulation Considerations for Solid Lipid Nanoparticles  DOI: 10.1208/s12249-015-0394-x
     , AAPS PharmSciTech, 17(3), 640-651, 2015
  • Munt, D. J., Grana, A., Hulce, M., Fusaro, R. M., Dash, A. K. Effect of Simultaneous Administration of Dihydroxyacetone on the Diffusion of Lawsone Through Various In Vitro Skin Models, AAPS PharmSciTech, (9 pages), 2015
  • Chandratre, S. S., Dash, A. K. Multifunctional nanoparticles for prostate cancer therapy, AAPS PharmSciTech, 16, 98-107, 2015
  • Dhapare, S. S., Dash, A. K. Effect of differential drying techniques on PLGA nanoparticles containing hydrophobic and hydrophilic anticancer agents, Therapeutic Delivery, 6, 27-39, 2015
  • Mistry, P. H., Mohapatra, S. K., Dash, A. K. Effect of high-pressure homogenization and stabilizers on the physicochemical properties of curcumin-loaded glycerol monooleate/chitosan nanostructures, Nanomedicine, 7, 1863-1876, 2012
  • Trickler, W. J., Munt, D. J., Jain, N., Joshi, S. S., Dash, A. K. Antitumor efficacy, tumor distribution and blood pharmacokinetics of chitosan/glyceryl-monooleate nanostructures containing paclitaxel, Nanomedicine, 6, 437-448, 2011
  • Pandit, A. A., Dash, A. K. Surface-modified solid lipid nanoparticulate formulation for ifosfamide: development and characterization, Nanomedicine, 6, 1397-1412, 2011
  • Trickler, W. J., Khurana, J., Nagvekar, A. A., Dash, A. K. Chitosan and Glyceryl Monooleate Nanostructures Containing Gemcitabine: Potential Delivery System for Pancreatic Cancer Treatment, AAPS PharmSciTech, 11, 392-401, 2010
  • Trickler, W. J., Nagvekar, A. A., Dash, A. K. The In vitro Sub-cellular Localization and In vivo Efficacy of Novel Chitosan/GMO Nanostructures containing Paclitaxel, Pharmaceutical research, 26, 1963-1973, 2009
  • Destache, C. J., Belgum, T., Christensen, K., Shibata, A., Sharma, A., Dash, A. Combination antiretroviral drugs in PLGA nanoparticle for HIV-1, BMC infectious diseases, 9, 198, 2009
  • Singh, S., Dash, AK Paclitaxel in Cancer Treatment: Perspectives and Prospects of its Delivery Challenges, Critical reviews in therapeutic drug carrier systems, 26, 333-372, 2009
  • Nagvekar, Ankita A., Trickler, William J., Dash, Alekha K. Current Analytical Methods Used in the In Vitro Evaluation of Nano-Drug Delivery Systems, Current Pharmaceutical Analysis, 5, 358-366, 2009
  • Singh, Somnath, Dash, Alekha K. Radioprotectants: basic concepts, current status and future directions, Drugs of the Future, 33, 681-689, 2008
  • Trickler, W. J., Nagvekar, A. A., Dash, A. K. A novel nanoparticle formulation for sustained paclitaxel delivery, AAPS PharmSciTech, 9, 486-493, 2008
  • Fernandes, P. P., Maniar, M., Dash, A. K. Development and validation of a sensitive liquid chromatographic method for the analysis of a novel radioprotectant: ON 01210.Na, Journal of Pharmaceutical and Biomedical Analysis, 43, 1796-1803, 2007
  • Jauhari, S., Dash, A. K. A mucoadhesive in situ gel delivery system for paclitaxel, AAPS PharmSciTech, 7, 53, 2006
  • Panyam, J., Williams, D., Dash, A., Leslie-Pelecky, D., Labhasetwar, V. Solid-state solubility influences encapsulation and release of hydrophobic drugs from PLGA/PLA nanoparticles, Journal of Pharmaceutical Sciences, 93, 1804-1814, 2004
  • Ganguly, S., Dash, A. K. A novel in situ gel for sustained drug delivery and targeting, International Journal of Pharmaceutics, 276, 83-92, 2004
  • Mo, Y., Dobberpuhl, D., Dash, A. K. A simple HPLC method with pulsed EC detection for the analysis of creatine, Journal of Pharmaceutical and Biomedical Analysis, 32, 125-132, 2003
  • Owens, H. M., Dash, A. K. Ceftriaxone Sodium: Comprehensive Profile, Profiles of Drug Substances, Excipients and Related Methodology, 20, 21-57, 2003
  • Dash, A. K., Sawhney, A. A simple LC method with UV detection for the analysis of creatine and creatinine and its application to several creatine formulations, Journal of Pharmaceutical and Biomedical Analysis, 29, 939-945, 2002
  • Chigurupati, N., Saiki, L., Gayser, C., Dash, A. K. Evaluation of red cabbage dye as a potential natural color for pharmaceutical use, International Journal of Pharmaceutics, 241, 293-299, 2002
  • Dash, A. K., Khin-Khin, A., Suryanarayanan, R. X-ray powder diffractometric method for quantitation of crystalline drug in microparticulate systems. I. Microspheres, Journal of Pharmaceutical Sciences, 91, 983-990, 2002
  • Dash, A. K., Mo, Y., Payne, A. Solid-state properties of creatine monohydrate, Journal of Pharmaceutical Sciences, 91, 708-718, 2002
  • Dash, A. K., Miller, D. W., Huai-Yan, H., Carnazzo, J., Stout, J. R. Evaluation of creatine transport using Caco-2 monolayers as an in vitro model for intestinal absorption, Journal of Pharmaceutical Sciences, 90, 1593-1598, 2001
  • Destache, C. J., Pakiz, C. B., Larsen, C., Owens, H., Dash, A. K. Cerebrospinal fluid penetration and pharmacokinetics of levofloxacin in an experimental rabbit meningitis model, Journal of Antimicrobial Chemotherapy, 47, 611-615, 2001
  • Fan, H. Y., Dash, A. K. Effect of cross-linking on the in vitro release kinetics of doxorubicin from gelatin un-plants, International Journal of Pharmaceutics, 213, 103-116, 2001
  • Dash, Alekha K., Brittain, Harry G. Correction: Mesalamine (Table 6 was missing), Analytical Profiles of Drug Substances and Excipients, 27, 379-381, 2001
  • Dash, A. K, Elmquist, W. F. Fluconazole, Analytical Profiles of Drug Substances and Excipients, 27, 67-113, 2001
  • Dash, A. K., Brittain, H. G. Mesalamine, Analytical Profiles of Drug Substances and Excipients, 25, 209-242, 1998

Presentations

  • Meerovich, I., Nichols, M.G., and Dash, A.K., Binary Liposomal Platform for the Low-Intensity Light-Induced Release of Doxorubicin, AAPS Annual Meeting and Exposition, San Antonio, TX, November 4-7, 2019.
     , 2019
  • Laliwala, A., Dash, A.K., Daverey, A., and Agrawal, S., α- tocopherol Loaded PLGA Nanoparticles for the Treatment of Spinal Cord Injury, AAPS Annual Meeting and Exposition, San Antonio, TX, November 4-7, 2019.
     , 2019
  • Munt, D., and Dash, A.K., A Comparison of the Permeability of Lidocaine Formulations Through a Shed Snake Skin Model of Stratum Corneum Using Franz Diffusion Chambers and an Air Interface Chamber, AAPS Annual Meeting and Exposition, San Antonio, TX, November 4-7, 2019.
     , 2019
  • Dash, S., Singh, S. and Dash, A.K., Injectable in-situ Gelling Metronidazole System for Treating Jawbone Infections, AAPS Annual Meeting and Exposition, San Antonio, TX, November 4-7, 2019.
     , 2019
  • Prabhu, S., and Dash, A.K., Development and Characterization of Nanoparticulate Delivery System for the Treatment of Cutaneous Melanoma, AAPS Annual Meeting and Exposition, San Antonio, TX, November 4-7, 2019.
     , 2019
  • Deodhar, S. and Dash, A.K., Preparation and Characterization of Poly(2-ethyl-2-oxazoline)-Lipid Conjugate as an Alternative to Polyethylene Glycol (PEG) for Surface Modified Long Circulating Liposomes, AAPS Annual Meeting and Exposition, Washington DC, November 4-7, 2018.
     , 2018
  • Munt, D.J. and Dash, A.K., Effect of Trisodium Citrate on the In Vitro Intestinal Permeability of Nutraceuticals. AAPS Annual Meeting and Exposition, Washington DC, November 4-7, 2018.
     , 2018
  • Laliwala, A., Dash, A.K., Daverey, A., and Agrawal, S., Vitamin E Loaded Calcium Alginate Nanoparticles for the Treatment of Spinal Cord Injury (SCI), AAPS Annual Meeting and Exposition, Washington DC, November 4-7, 2018
     , 2018
  • Meerovich, I, Nichols, M., and Dash, A.K., Solid-Lipid Nanoparticles Based on Unsaturated Lipids for Controlled Drug Release of Paclitaxel, AAPS Annual Meeting and Exposition, Washington DC, November 4-7, 2018.
     , 2018
  • Meerovich, I, Nichols, M., and Dash, A.K., Role of Ascorbic Acid as a Hydrophilic Antioxidant in Solid-Lipid Nanoparticles with Photooxidation-Based Drug Release, AAPS Annual Meeting and Exposition, Washington DC, November 4-7, 2018.
     , 2018
  •  Arsiwala, T. and Dash, A.K., A Comparative Study of Two Liposomal Delivery Systems Targeted for Glioblastoma Multiforme, AAPS Annual Meeting and Exposition, Washington DC, November 4-7, 2018.
     , 2018
  • Arsiwala, T. and Dash, A.K., The Effect of Freeze Thaw Cycles on the Phospholipid Bilayer of a Unilamellar Liposome Evaluated by 31P NMR and Cryo-TEM, AAPS Annual Meeting and Exposition, Washington DC, November 4-7, 2018.
     , 2018
  • Nayak, R, Dash A.K. and Singh, S., Preparation and Characterization of a Reactive Oxygen Species (ROS)-Triggered Nano Delivery System containing Memantine and Celecoxib, AAPS Annual Meeting and Exposition 2018, Washington DC, November 4-7, 2018.
     , 2018
  • Singh, S. and Dash A.K., Developing Sustained Release Delivery Systems for Hydrogen Sulfide: Influence of Dissolved Oxygen in Releasing Media and its temperature, AAPS Annual Meeting and Exposition 2018, Washington DC, November 4-7, 2018.
     , 2018
  • Misra, B., Tolman, J., Dash, A.K., Modified Release of Microparticles for Pulmonary Drug Delivery, AAPS Annual Meeting and Exposition 2017, San Diego, CA, November 12-15, 2017.
     , 2017
  • Verma, R., Dash, A.K. Singh, S., A Novel Microparticle-Based In Situ Gelling System For Sustained Delivery of Hydrogen Sulfide, AAPS Annual Meeting and Exposition 2017, San Diego, CA, November 12-15, 2017.
     , 2017
  • Nayak, R., Dash, A.K. Singh, S., The Simultaneous Quantification of Celecoxib and Memantine in aqueous phase by LC-MS/MS, AAPS Annual Meeting and Exposition 2017, San Diego, CA, November 12-15, 2017.
     , 2017
  • Deodhar, S., Dash, A.K., North, E.J., Meerovich, I., Liposomal Delivery of Gemcitabine and Irinotecan in Pancreatic Ductal Adenocarcinoma, AAPS Annual Meeting and Exposition 2017, San Diego, CA, November 12-15, 2017.
     , 2017
  • Arsiwala, T. and Dash, A.K., Preparation and Characterization of an Optimized Liposomal Delivery System for Temozolomide, Elacridar And RG7388 to Treat Glioblastoma Multiforme, AAPS Annual Meeting and Exposition 2017, San Diego, CA, November 12-15, 2017., 2017
  • Munt, D. J., Xin, X., Dash, A.K., Physicochemical Characterization of Disodium Creatine Phosphate, AAPS Annual Meeting and Exposition 2017, San Diego, CA, November 12-15, 2017.
     , 2017
  • Munt, D. J., Xin, X., Dash, A.K., Toxicity and Mutagenicity of Disodium Creatine Phosphate and Development of a Stability Indicating HPLC Method for the Simultaneous Analysis of Creatine and Creatinine, AAPS Annual Meeting and Exposition 2017, San Diego, CA, November 12-15, 2017.
     , 2017
  • Meerovich, I. and Dash, A.K., Paclitaxel-loaded Solid Lipid Nanoparticles with Photo-Induced Drug Release, AAPS Annual Meeting and Exposition 2017, San Diego, CA, November 12-15, 2017.
     , 2017
  • Saralkar, P.A. and Dash, A.K., Curcumin and Resveratrol Loaded Calcium Alginate Nanoparticles for Anti-Cancer Therapy, AAPS Annual Meeting and Exposition 2016, Denver, CO, November 12-17, 2016.
     , 2017
  • Bose, S. and Dash, A.K., Preparation and Characterization of Contact Lenses for Ocular Drug Delivery, AAPS Annual Meeting and Exposition 2016, Denver, CO, November 12-17, 2016.
     , 2016
  • Meerovich, I, Dash, A.K., and Nichols, M., Near-Infrared Light-Induced Drug Release from Solid Lipid Nanoparticles, AAPS Annual Meeting and Exposition 2016, Denver, CO, November 12-17, 2016.
     , 2016
  • Bhujbal, S. and Dash, A.K., Metformin loaded hyaluronic acid nanoparticles for oral delivery, AAPS Annual Meeting and Exposition 2016, Denver, CO, November 12-17, 2016.
     , 2016
  • Patil, A., Verma, R., Dash, A., and Singh, S. Development and Validation of a Simple HPLC Method for Quantification of GYY 4137 – A Hydrogen Sulfide Donor, AAPS Annual Meeting and Exposition 2016, Denver, CO, November 12-17, 2016.
     , 2016
  • Patil, A., Dash, A., Opere, C., and Singh, S., Preparation, Characterization and Toxicity Evaluation of a Novel Controlled Release Delivery System for a Hydrogen Sulfide Donor - GYY 4137, AAPS Annual Meeting and Exposition 2016, Denver, CO, November 12-17, 2016.
     , 2016
  • Siracuse, B., Meerovich, I, Dash, A.K., and Nichols, M. In vitro Release of Dexamethasone from Photosensitized Solid-Lipid Nanoparticles Upon Laser Illumination at Near-Infrared Range, CURAS Research Forum, Creighton University, Omaha, NE, October 5, 2016.
     , 2016
  • Munt, D., and Dash, A.K., Development and Validation of a Novel Air Interface Diffusion Cell for Evaluating the Diffusion of Diclofenac from Topical Spray Formulations, AAPS Annual Meeting and Exposition 2015, Orlando, FL, October 25-29, 2015.
     , 2015
  • Bhujbal, S., and Dash, A.K., Preparation and Characterization of Metformin-Loaded Hyaluronic Acid Nanoparticles, AAPS Annual Meeting and Exposition 2015, Orlando, FL, October 25-29, 2015.
     , 2015
  • Meerovich, I., Dash, A.K., Nicholas, M., Smith, D., Localized Near-Infrared Light-Induced Drug Release from Liposomes, AAPS Annual Meeting and Exposition 2015, Orlando, FL, October 25-29, 2015.
     , 2015
  • Meerovich, I., Dash, A.K., Smith, D., Targeting Chitosan Particles to Tumor Cells by Direct Solid Phase Peptide Synthesis, AAPS Annual Meeting and Exposition 2015, Orlando, FL, October 25-29, 2015.
     , 2015
  • Saralkar, P., and Dash, A.K., Biodegradable Calcium Alginate Nanoparticles for Anti-Cancer Therapy, AAPS Annual Meeting and Exposition 2015, Orlando, FL, October 25-29, 2015.
     , 2015
  • Pandey, S, and Dash, A.K., Preparation and Characterization of Drug Loaded Multifunctional Chitosan Microparticles for Lung Cancer Targeting, AAPS Annual Meeting and Exposition 2015, Orlando, FL, October 25-29, 2015.
     , 2015
  • Patil, A., Dash, A.K., and Singh, S., Development and Validation of a Simple HPLC Method for Quantification of Hydrogen Sulfide (H2S) in Aqueous Samples, AAPS Annual Meeting and Exposition 2015, Orlando, FL, October 25-29, 2015.
     , 2015
  • Dash, A.K., Pandey, S. Preparation and Characterization of Multifunctional Chitosan Microparticles for Lung Delivery, AAPS Annual Meeting and Exposition 2014, San Diego, CA, November 6, 2014.
     , 2014
  • Meerovich, I., Dash, A.K., Hulce, M., Smith, D. Direct Solid Phase Peptide Synthesis on Chitosan Microparticles for Tumor Targeting, AAPS Annual Meeting and Exposition 2014, San Diego, CA, November 6, 2014.
     , 2014
  • Dash, A.K., Grana, A., Munt, D., Characterization of a Multiple Emulsion for Topical Application of Dihydroxyacetone and Lawsone, AAPS Annual Meeting and Exposition 2014, San Diego, CA, November 3, 2014.
     , 2014
  • Dash, A.K., Grana, A., Munt, D., Rheological Examination of a Multiple Emulsion for Topical Application of Dihydroxyacetone and Lawsone, AAPS Annual Meeting and Exposition 2014, San Diego, CA, November 3, 2014.
     , 2014
  • Munt, D., Dash, A.K. Development and Evaluation of Spray Pattern Analysis for Topical Dual Spray Formulations, AAPS Annual Meeting and Exposition 2014, San Diego, CA, November 3, 2014.
     , 2014
  • Singh, V., Propst, S., Munt, D., Dash, A.K., Multifunctional Ethylcellulose Microparticles Containing Iron Oxide Nanoparticles for Hyperthermic Cancer Therapy, AAPS Annual Meeting and Exposition 2013, San Antonio, TX, November 10- 14, 2013.
     , 2013
  • Singh, V., Munt, D., Dash, A.K., Effect of External Radiofrequency on the In Vitro Release of Drug from Thermoresponsive Polymer Coated Iron Oxide Nanoparticles, AAPS Annual Meeting and Exposition 2013, San Antonio, TX, November 10- 14, 2013.
     , 2013
  • Grana, A., Munt, D., Dash, A.K., Preparation and Characterization of a Stable Microemulsion for Topical Application of DHA and Lawsone, AAPS Annual Meeting and Exposition 2013, San Antonio, TX, November 10- 14, 2013.
     , 2013
  • Chandratre, S., Dash, A.K., Preparation and Characterization of Multifunctional Solid-Lipid Nanoparticles for Cancer Therapy, AAPS Annual Meeting and Exposition 2013, San Antonio, TX, November 10- 14, 2013.
     , 2013
  • Dhapare, S., Dash, A.K., Development and Characterization of PLGA Nanoparticles Containing Paclitaxel and Gemcitabine for Combination Therapy, AAPS Annual Meeting and Exposition 2013, San Antonio, TX, November 10- 14, 2013.
     , 2013
  • Dhapare, S., Dash, A.K., Evaluation of Cellular Uptake, Cytotoxicity and Hemolytic Effects of PLGA Nanoparticles Containing a Combination of Anticancer Agents Paclitaxel and Gemcitabine, AAPS Annual Meeting and Exposition 2013, San Antonio, TX, November 10- 14, 2013.
     , 2013
  • Dhapare, S., Dash, A.K., Preparation and Characterization of Dual Function Nanoparticles Intended for Targeting Cancer Stem Cells, St. Albert’s Day Student Research Forum, Creighton University, March 26, 2013.
     , 2013
  • Dhapare, S., Dash, A.K., Further Studies on Preparation and Characterization of PLGA Nanoparticles Containing Hydrophobic and Hydrophilic Drugs, St. Albert’s Day Student Research Forum, Creighton University, March 26, 2013.
     , 2013
  • Dhapare, S., Dash, A.K., Fabrication and Characterization of PLGA Nanoformulation System Containing Both Hydrophobic and Hydrophilic Drugs, AAPS Annual Meeting and Exposition 2012, Chicago, IL, October 14-October 18, 2012.
     , 2012
  • Dhapare, S., Chandratre, S., Dash, A.K., Cellular Uptake and Cytotoxicity of Nanoparticles Containing Both Hydrophilic and Hydrophobic Drugs, AAPS Annual Meeting and Exposition 2012, Chicago, IL, October 14-October 18, 2012.
     , 2012
  • Singh, V., Dash, A.K., Preparation, Characterization, and Evaluation of the Effect of Radiofrequency Application on Glyceryl-Monooleate (GMO)-Iron Oxide Nanoparticles, AAPS Annual Meeting and Exposition 2012, Chicago, IL, October 14-October 18, 2012.
     , 2012
  • Chandratre, S., Chauhan, H., Dash, A.K., Crystallization Inhibition of GMO-Chitosan Nanoparticles During Lyophilization Process, AAPS Annual Meeting and Exposition 2012, Chicago, IL, October 14- October 18, 2012.
     , 2012
  • Chandratre, S., Dash, A.K., Effect of Method of Preparation, and Stabilizer on the Stability of Glyceryl Monooleate-Chitosan Nanoemulsion, AAPS Annual Meeting and Exposition 2012, Chicago, IL, October 14-October 18, 2012.
     , 2012
  • Munt, D., Dash, A.K.; Hulce, M.; Fussaro, R., Permeability of DHA and the Effect of DHA on the Permeability of Lawsone Across a Pig Skin, AAPS Annual Meeting and Exposition 2012, Chicago, IL, October 14-October 18, 2012.
     , 2012
  • Munt, D., Fusaro, R., Hulce, M., Dash, A.K., Permeability of Dihydroxyacetone and its Effect on the Transport of Lawsone Across a Snake Skin Model for Stratum Corneum, AAPS Annual Meeting and Exposition 2011, Washington DC, October 23-October 27, 2011.
     , 2011
  • Mohapatra, S., Dash, A.K., Influence of High Pressure Homogenization, Hydrophobic Drug Load, and Stabilizers on the GMO/Chitosan Nanoemulsion Particle Characteristics, AAPS Annual Meeting and Exposition 2011, Washington DC, October 23-October 27, 2011.
     , 2011
  • Mohapatra, S., Kadajji, V.G., Goede, M., Destache, C.J., Dash, A.K., Combination Ativiral Vaginal Gels for Prophylactic Treatment of HIV-1, AAPS Annual Meeting and Exposition 2011, Washington DC, October 23-October 27, 2011.
     , 2011
  • Mohapatra, S., Mistry, P., Dash, A.K., A Novel Approach for the Preparation of a Stable GMO/Chitosan Nanoemulsion Containing Paclitaxel, AAPS Annual Meeting and Exposition 2011, Washington DC, October 23-October 27, 2011.
     , 2011
  • Gupte, M.P., Dash, A.K., Development and Validation of an Efficient UPLC Method for the Analysis of Methylglyoxal, AAPS Annual Meeting and Exposition 2011, Washington DC, October 23-October 27, 2011.
     , 2011
  • Mohapatra, S., Dash, A.K., Rheological Characterization of a Combinational Antiviral Vaginal Gel Formulation, AAPS Annual Meeting and Exposition 2011, Washington DC, October 23-October 27, 2011.
     , 2011
  • Chauhan, H., Mohapatra, S., Mistry, P., Munt, D., Dash, A.K., Physical Characterization of Glyceryl Monooleate (GMO) During Lyophilization Process, AAPS Annual Meeting and Exposition 2011, Washington DC, October 23-October 27, 2011.
     , 2011
  • Mistry, P., Dash, A.K., Surface Modified Solid-Lipid Curcumin Nanoparticles for Oral Delivery, AAPS Annual Meeting and Exposition 2011, Washington DC, October 23-October 27, 2011.
     , 2011
  • Gupte, M.P., Dash, A.K., Effect of Cross-Linker on GMO/Chitosan Nanoparticulate System Containing a Hydrophilic Drug, AAPS Annual Meeting and Exposition 2011, Washington DC, October 23- October 27, 2011.
     , 2011
  • Pandit, A., Dash, A.K., Development and Characterization of Sustained-Release Delivery System for Hydrophilic Drug: Ifosfamide. AAPS Annual Meeting and Exposition 2010, New Orleans, LA, November 14-November 18, 2010.
     , 2010
  • Hanna, P.A., Dash, A.K., Multiparticulate Alginate Delivery System for Targeting and Sustaining Drug via Oral Delivery. AAPS Annual Meeting and Exposition 2010, New Orleans, LA, November 14- November 18, 2010.
     , 2010
  • Hanna, P.A., Dash, A.K., Evaluation and Optimization of Alginate Microparticulate Delivery System for Drug Targeting. AAPS Annual Meeting and Exposition 2010, New Orleans, LA, November 14- November 18, 2010.
     , 2010
  • Kadajji, V., Dash, A.K., Polymeric Nanoparticles of Gamma Tocotrienol for Sustained Delivery in Radioprotective Therapy. AAPS Annual Meeting and Exposition 2010, New Orleans, LA, November 14- November 18, 2010.
     , 2010
  • Gupte, M.P., Dash, A.K., Effect of Drug Loading of Methylglyoxal on the Physicochemical Properties of GMO-Chitosan Nanoparticles. AAPS Annual Meeting and Exposition 2010, New Orleans, LA, November 14-November 18, 2010.
     , 2010
  • Pandit, A., Mistry, P., Dib, P., Nikolaidis, A., Dash, A.K., Dissolution Profiles of Creatine Nitrate, Creatine Monohydrate and Buffered Creatine. AAPS Annual Meeting and Exposition 2010, New Orleans, LA, November 14-November 18, 2010.
     , 2010
  • Pandit, A., Mistry, P., Dib, P., Nikolaidis, A., Dash, A.K., Chemical Stability of Creatine Nitrate, Creatine Monohydrate and Buffered Creatine in Solution. AAPS Annual Meeting and Exposition 2010, New Orleans, LA, November 14-November 18, 2010.
     , 2010
  • Pandit, A., Mistry, P., Dib, P., Nikolaidis, A., Dash, A.K., Equilibrium Solubility Studies of Creatine Nitrate, Creatine Monohydrate and Buffered Creatine. AAPS Annual Meeting and Exposition 2010, New Orleans, LA, November 14-November 18, 2010.
     , 2010

Research and Scholarship

Research and Scholarship Interests

  • Design and Evaluation of Novel Drug Delivery Systems, Preformulation Studies, Solid-State Characterization of Drugs and Dosage Forms, Pharmaceutical Analysis Utilizing the Following Techniques: HPLC, GC, GC-MS, Thermoanalytical methods, IR, Powder X-ray Diffraction and Scanning Electron Microscopy, and Evaluation and Design of Dosage Forms for Nutraceuticals

Grant Funding Received

  • Dash A.K. (Co-PI) and Dravid, S. (PI), A high throughput multi-user Biacore surface plasmon resonance system for studying biomolecular and biochemical interactions.
  • Dash, A.K., Analysis of Phenolic Extracts and their Oral Permeability, Phenolics LLC, Omaha, NE
  • Dash, A.K., Development, validation and analysis of creatine and leucin in plasma samples, Phenolics LLC, Omaha, NE
  • Dash A.K. Omaha Family Foundation Award matching fund for the purchase of a GPC system
  • Dash, A.K., Disodium Phosphocreatine: Evaluation of its Physicochemical Properties and Permeabilitys, Phenolics LLC, Omaha, NE
  • Dash, A.K., Evaluation of Leucine Permeability Studies, Phenolics LLC, Omaha, NE
  • Dash A.K. Omaha Family Foundation Award for the purchase of ERWEKA–All Purpose R&D Equipment–Model AR 403
  • Dash A.K. Robert B. Daugherty Foundation Capital Project Award for the purchase of a LC-MS-MS (API 5500 Q-trap)
  • Dash, A.K., Thermal Analysis and Evaluation of Crystal Growth at a Low Temperature on Some Pet Care Products, Sergent’s Pet Care Products Co.
  • Dash, A.K. (Co-PI) and Venkatesh Govindarajan (PI), Acquired Resistance to Targeted Therapy in Mucinous Colorectal Cancers. LB595 Grant
  • Dash, A.K., Evaluation of Creatine Permeability Studies, Phenolics LLC, Omaha, NE
  • Dash, A.K., Evaluation of Various Chewable Tablet Formulations, Fitzpatrick, Cella, Harper & Scinto
  • Dash, A.K., Evaluation of Vacuant vs Enemeez, Alliance Labs LLC
  • Dash, A.K., Use of Pharmaceutics in the Development of Pet Care Products, Sergent’s Pet Care Products Co.
  • Dash, A.K. (CO-PI) and Govindarajan V., PMP: Biologic Foundations for New Treatment Option, National Organization of Rare Disorders (NORD)
  • Dash, A.K., President’s Faculty Research Fund, Novel Skin-bound Melanoidins-Sunscreen a Delivery Approach to Melanoma Prevention
  • Dash, A.K., LB 692 New Initiatives Research Grant Program, State of Nebraska Cancer & Smoking Grant, Nanome™: A Novel Nanodelivery System for Tumor Targeting
  • Dash, A.K., Thermolife International, Creatine Nitrate solubility and stability

Awards and Honors

  • Mucoadhesive Nanoparticles For Cancer Treatment (A. Dash and W. Trickler) Filled on October 26, 2006. Issued US Patent 20100323977., 2007
  • Hydroxyapatite Based Drug Delivery Implant for Cancer Treatment; US Patent # 6767550, July 2004., 2004
  • Trademark registration (Reg. No. 3,687,057) on “NANOME™”. Registered on Sept 22, 2009., 2009
  • USAID Consultant to Armenia, 2013
  • Department of Pharmaceutics, Faculty of Pharmacy, Kuwait University, 2012
  • Healthway Pharmacy Technology, MD, 2008
  • Academic Excellence Award-2019, Association of Pharmacy Professionals (APP), India, 2020
  • US Patent Application No. 15/237,826 - Non-Provisional Application Filed on 8/16/2016. Composition and Method for Preparing Multifunctional Targeting Complexes, Inventors Igor Meerovich, Alekha Dash and D. David Smith., 2016
  • Provisional Patent Application (#62397750) filled on 3/14/2016. Diffusion Cells, Inventors Daniel Munt and Alekha Dash., 2016
  • Foam-Film System with Antibacterial Properties and Methods for Reducing Bacterial Contamination in Animal Carcasses, Filed on November 15, 2003. International Application #: PCT/US04/038094., 2003